Vertical Laminar Air Flow (Stand Mounted VLAF)
Engineered to establish an ultra-clean localized ISO Class 5 / Class 100 sterile working zone for sensitive pharmaceutical compounding, microbiology research, and sterile preparation. High-velocity unidirectional vertical airflow shields products against airborne cross-contamination.
Engineering Overview & Fluid Dynamics
Active contamination barrier and laminar downflow principles
The Himalayan Steel Vertical Laminar Air Flow (VLAF) workstation supplies unidirectional, uniform downward laminar airflow over an entire stainless steel work table at 0.45 ± 0.1 m/s. Room air enters via bottom pre-filters and is propelled through high-efficiency mini-pleat H14 HEPA filters located above the workspace. Because the air travels downwards through perforated work surfaces or exits via the front operator aperture, product protection is maximized while preventing cross-batch contamination.
Technical Engineering Specifications
Standard dimensional tolerances, electrical parameters, and air quality ratings
Standard Dimensional Matrix
Fabrication schedule comparison in Imperial and Metric standards
| Size (Feet) | Metric (MM) | Internal Chamber (W x D x H) | External Footprint (W x D x H) |
|---|---|---|---|
| 2 x 2 ft | 610 x 610 x 1800 mm | 610 x 610 x 650 mm | 760 x 780 x 1950 mm |
| 3 x 2 ft (Standard Lab) | 915 x 610 x 1800 mm | 915 x 610 x 650 mm | 1065 x 780 x 1950 mm |
| 4 x 2 ft (Pharma Benchmark) | 1220 x 610 x 1800 mm | 1220 x 610 x 650 mm | 1370 x 780 x 1950 mm |
| 5 x 2 ft | 1524 x 610 x 1800 mm | 1524 x 610 x 650 mm | 1675 x 780 x 1950 mm |
| 6 x 2 ft (Dual Operator) | 1830 x 610 x 1800 mm | 1830 x 610 x 650 mm | 1980 x 780 x 1950 mm |
Cleanroom Construction & Architectural Design
cGMP sanitary fabrication details from our Baddi engineering works
The primary work bed is laser-cut from high-purity AISI 316L stainless steel, dished slightly to contain liquid accidental spills, and electropolished to Ra < 0.4 µm.
Dynamically balanced backward curved centrifugal blowers installed on elastomer vibration dampening isolators to prevent micro-vibrations during micro-pipetting.
Precision mechanical compression jacks apply even upward pressure against the fluid gel channel of the mini-pleat HEPA filter for absolute leak-tight sealing.
Upstream aerosol injection port and challenge sample port located right on the front face for convenient calibration without moving the equipment.
Smooth slide-balanced tempered safety glass with optical sash height sensors that trigger an alarm if opened beyond recommended operating aperture.
Welded tubular 304 SS tubular stand fitted with dual-locking polyurethane swivel castors and heavy-gauge vibration pads for solid stationary placement.
Standard Operating Protocol (cGMP SOP)
Standard operating guidelines and contamination control sequence
Step-by-Step Material Transfer Sequence
Sanitization & Wipe-Down Protocol
- Wipe worktable before and after every batch using 70% IPA and sterile lint-free wipes.
- Clean acrylic / glass sashes with non-abrasive cleanroom detergent.
- Inspect and wash suction pre-filters monthly in purified water.
Fail-Safe Interlock Protection
- UV lamp automatically shuts off if the front sliding sash is opened.
- Audio-visual buzzer alarms if airflow drops below 0.35 m/s.
Optional Engineering Customizations
Site-specific hardware adaptations
- Gas / vacuum service cock fittings with safety shut-off valves
- Stainless steel intravenous (IV) infusion hanging bar with hooks
- Front stainless steel armrest bar for operator ergonomic wrist support
- Static-neutralizing ionizer bar for particulate elimination on plastics
- Variable speed fan controller with auto air velocity compensation
- FLAMEPROOF motor blower assembly for solvent-rich laboratories
Quality Validation Package (DQ/IQ/OQ)
Audit-ready documentation for US FDA and EU-GMP inspections
- Design Qualification (DQ) Documentation & Mechanical GA Drawings
- Installation Qualification (IQ) Protocol Checklists
- Operational Qualification (OQ) Velocity Mapping & Test Records
- HEPA Filter Integrity Scan Certificate (DOP/PAO < 0.01%)
- Non-Viable Particle Count Certificate (ISO Class 5 Compliance)
- Electrical Safety & High Voltage Flash Test Certificate
Cleanroom Design Highlights
- Unidirectional downward airflow sweeps particulates away from sensitive sterile products
- Seamless SS 316L worktop with coved corners prevents microbial colonization
- Feather-touch soft control switches for blower, LED lighting, and germicidal UV-C tube
- Lockable heavy-duty polyurethane caster wheels with integrated leveling foot studs
Target Pharmaceutical Applications
Explore Other Equipment Divisions
Horizontal Laminar Air Flow Clean Bench (HLAF)
Horizontal crossflow ISO Class 5 clean bench with back-to-front laminar protection, HEPA H14 filtration, and SS 304/316 worktable.
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Overhead suspended sterile downflow hood for aseptic filling lines, vial conveyor shielding, and reactor vessel transfers.
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